Article: Final Report on Opioid Dependence Now Available

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Posted on July 22, 2014 by Comparative Effectiveness Public Advisory Council (CEPAC)

New England CPAC has released a final evidence report on management options for patients with opioid use disorder. The final report incorporates findings from a recent public meeting of the New England CEPAC, where council members reviewed evidence on the effectiveness and value of different management approaches for opioid use disorder and made recommendations to guide practice and policy.  The key findings of the review and votes of CEPAC found that treatment programs that use a medication like methadone to replace the opioid (a method known as maintenance therapy) are more effective than short-term managed withdrawal approaches that attempt to discontinue all opioid use (sometimes referred to as detoxification).  Short-term withdrawal management programs typically focus on weaning patients off opioids within a 30-day timeframe, while maintenance programs assume patients will remain on medication for longer periods of time.

Click here to read the “Management of Patients with Opioid Dependence : A Review of Clinical, Delivery System, and Policy Options” Final Report that compares common approaches to opioid dependence treatment, offers insight into which management options provide the best outcomes for patients and how the options compare from a budget impact and cost-effectiveness perspective. The review focuses on three key pharmacologic interventions: methadone, buprenorphine/Suboxone®, and naltrexone.